United States - MEX-AD:Clinical, epidemiological, & genetic characterization of Alzheimer's patients in the admixed Mexican population

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Details

Provided by Open Opps
Opportunity closing date
26 February 2024
Opportunity publication date
12 January 2024
Value of contract
to be confirmed
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Description

The purpose of this requirement is to establish a multicentre cohort study in Mexico and characterize Alzheimer's
disease (AD) patients' clinical, genetic, and phenotypic diversity in the admixed Mexican population, a group with
unique genetic admixture and environmental exposures that is underrepresented in AD research.
First, the Contractor shall determine the genetic substructure and familial contributions to AD in Mexico. This will
advance efforts to treat AD in patients with rare mutations.

Second, by assembling this large cohort, the Contractor shall work to establish a preliminary Mexican-specific
polygenic risk score (PRS) for predicting AD risk in future samples.
Please see attached RFP titled "75N95024R00016 Solicitation" for the full solicitation.

Opportunity closing date
26 February 2024
Value of contract
to be confirmed

About the buyer

Address
NATIONAL INSTITUTES OF HEALTH NIDA UNITED STATES
Contact
hashim.dasti@nih.gov

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